Ark Therapeutics Group Plc said that a Phase 3 study of its gene therapy for brain cancer reached its primary endpoint. The multi-centre trial was undertaken at the request of the European Medicines Agency to confirm the safety and efficacy of the treatment, which is known as Cerepro.
GPC Biotech AG said that the European marketing authorisation application for its cancer drug, satraplatin, is being withdrawn following a review at the European Medicines Agency which indicated the drug is not approvable.
MorphoSys AG, which specialises in developing antibody-based drugs, reported that its half-year revenues rose by 16% to €33.3 million from the year-earlier period while its net profit tripled to €6.3 million from €2 million.
One of the UK’s most promising vaccine developers, Acambis Plc, has agreed to be acquired by Sanofi Pasteur Holding in an all-cash deal valued at £276 million.
Four days after announcing its first ever research agreement with the University of Cambridge in the UK, GlaxoSmithKline has disclosed a five-year collaboration with the Harvard Stem Cell Institute in the US to discover new therapies based on stem cell science.
The main scientific committee of the European Medicines Agency (EMEA) is recommending that two new medicines for use in surgical settings be granted marketing authorisations in Europe. But it has rejected an application for a new therapy to treat an inherited disorder known as Friedreich’s Ataxia. In a third decision, it reversed an earlier negative opinion for an orphan drug for adults with acute myeloid leukaemia.
Roche said that it has agreed to pay C$191 million in cash for a Canadian biotechnology company, ARIUS Research Inc, which has developed a new antibody platform.
The European Medicines Agency has recommended restrictions on the oral use of medicines containing norfloxacin for the treatment of urinary infections.
Roche said that it has reached an agreement to take over the privately-owned Mirus Bio Corporation of Madison, Wisconsin, for $125 million in order to gain access to the company’s RNAi delivery technology.
GlaxoSmithKline has signed its first ever research agreement with the University of Cambridge in the UK to develop a novel, centrally-acting agent with therapeutic potential for obesity and addictive disorders. Financial terms were not disclosed.