UK-based Crescendo Biologics Ltd has secured its first commercial deal since its founding in 2007 with the signing of a collaboration and license option agreement with Takeda Pharmaceutical Company Ltd. The deal concerns several preclinical drug candidates that have been derived from the VH antibody domains of transgenic mice.
Patients with head and neck cancer who were treated with nivolumab experienced a better quality of life than those treated with chemotherapy, according to an outcomes study released on 9 October at the European Society for Medical Oncology congress in Copenhagen.
France-based Innate Pharma SA said data from a Phase 1 study of its antibody lirilumab administered with nivolumab to patients with refractory solid tumours, showed a similar safety profile to that of nivolumab alone. The data were presented on 9 October at ESMO.
A study by clinicians at the Universities of Leuven and Ghent in Belgium, together with the University of Oxford, has shown that better use of a point-of-care diagnostic can help general practitioners determine which children need hospitalisation because of a serious disease and which can remain at home.
Researchers at Vienna’s Institute of Molecular Biotechnology (IMBA) and the Max F Perutz Laboratories (MFPL) have discovered a new mechanism for unleashing the immune system to kill fungal pathogens. Their research was published in the journal Nature Medicine.
Sanofi SA has received a second multi-million dollar contract from the US government’s biomedical advanced research and development authority (BARDA) for research into new medicinal products – this time for a product to treat acute radiation syndrome in the event of a public health emergency.
Newron Pharmaceuticals SpA, an Italian biotech with a Zurich listing, has raised CHF 26.1 million (€23.8 million) with a private equity placement, which will help cover marketing and research and development costs through 2018.
Alnylam Pharmaceutials Inc, the world’s leading developer of therapies based on RNA interference (RNAi) , has stopped development of revusiran, a treatment for a hereditary amyloidosis with cardiomyopathy, a condition caused by the abnormal accumulation of amyloid proteins in the body.
A collaborative research project between scientists at the University of Texas MD Anderson Cancer Center and Karus Therapeutics Ltd, a venture capital-backed company in the UK, has yielded a candidate drug inhibiting P13K, a target of growing interest to the pharmaceutical industry.
Yoshinori Ohsumi, a professor at the Tokyo Institute of Technology, has been awarded the 2016 Nobel Prize in Physiology or Medicine for his work in discovering and elucidating the mechanisms underlying autophagy, a process by which the cell can degrade and recycle its own contents.