A Phase 3 trial of the small molecule drug elafibranor failed to meet its primary endpoint in adults with non-alcoholic steatohepatitis (NASH), the developer Genfit SA announced on 11 May. The trial was attempting to show a resolution of NASH without a worsening of fibrosis. The response rate among the 717 patients who were tested was 19.2% for those in the elafibranor group compared with 14.7% for patients on a placebo.
